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Description
As for transcobalamin II deficiency, an observational case series of 30 patients revealed that IM administration of 1 mg of OH-Cbl or CN-Cbl weekly for a lifetime appears to be a suitable treatment regimen ( TABLE 2 Formulation and dosage regimes for treatment of vitamin B12 deficiency, subdivided into congenital and acquired causes
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doi:10.1093/advances/nmy023
While cobalamin overdose is unheard of because it is non-toxic and water-soluble, cobalamin deficiency can happen due to a number of reasons, including certain diseases and genetic defects.
