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Possible link between genes found dysregulated and key events described in neuro-related AOPs The observed transcriptional and functional developmental neurotoxic effects described in this study are in line with mechanistic knowledge described in COVID-19 relevant AOPs under development in the context of the CIAO project [119], [120], [121] and in other neuro-related AOPs

A suspension of zoospores (#87) was collected from actively growing flasks, filtered through a 10 M syringe filter (Millipore), centrifuged, then added to 96 well plates at 5 10 4 zoospores in TGhL per well with 10 M 2-AAPA, or 0.05% DMSO control

Apply a thin layer to clean, dry skin