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When PNP was inhibited pharmacologically by the compound immucillin H (ImmH), intracellular cleavage of NR to NAM was prevented, and NAD + synthesis was potentiated from NR both in vitro and in vivo 25

Pernicious anemia is an autoimmune disorder that prevents the absorption of vitamin B12 due to a lack of intrinsic factora protein produced by the stomach lining

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