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Ingredients Water, Butylene Glycol, Glycerin, Methylpropanediol, Niacinamide, Propanediol, 1,2-Hexanediol, Betaine, Carbomer, Hydroxyacetophenone, Tromethamine, Glycereth-25 PCA Isostearate, Sea Water, Diphenyl Dimethicone, Panthenol, Triethylhexanoin, Ethylhexylglycerin, Xanthan Gum, Adenosine, Disodium EDTA, Fragrance, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Biosaccharide Gum-1, Glutathione, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium DNA, Sodium Hyaluronate, Stellaria Media (Chickweed) Extract, Lactobacillus Ferment, Aloe Barbadensis Leaf Extract, Dioscorea Japonica Root Extract, Hibiscus Esculentus Fruit Extract, Malva Sylvestris (Mallow) Extract, Saccharide Isomerate, Alanine, Glutamic Acid, Glycine, Serine, Threonine, Calendula Officinalis Flower Extract, PCA, Hamamelis Virginiana (Witch Hazel) Leaf Extract, Centella Asiatica Extract, Citric Acid, Sodium Citrate, Ascorbic Acid, Helianthus Annuus (Sunflower) Seed Oil, Tranexamic Acid, Caprylic/Capric Triglyceride, Ceramide NP

FIGURE 1 3.2.2 CSD theory Trigeminal afferent activation sets off the pain pathway, which sends information to the TG, the TNC, and finally to the brainstem and cortical structures involved in pain processing, resulting in pain (Zhang et al., 2011)

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