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In normal smokers, there is an increase in AP sites in the lungs, signifying active DNA repair, but this is significantly reduced in COPD patients, showing defective DNA repair in COPD

The absorbance was measured at 450 nm using an enzyme marker (BioTek, Gen 5), and the growth rate of cells was calculated as follows: where A blank is the absorbance of the wells without cells, and A control and A test are the absorbances of the control and treated cells, respectively

Author Contributions Conceptualization, S.G

In addition, DNL was independently associated with intrahepatic triglyceride levels [39], and inadequate suppression of DNL during fasting could be a key feature in NAFLD patients [38, 39]