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Description
Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro
After neoadjuvant chemotherapy (NACT), TAMs showed increased expression of pro-inflammatory pathways, including activation of the inflammasome and secretion of cytokines like IL-1, which can promote T-cell activation and enhance the overall immune response against the tumor
Highlighting the importance of 2OG to T cell transcriptional reprogramming, 2OG regulates roughly a third of all IL-2-induced genes
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