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Similarly, oxaliplatin induces persistent mechanical allodynia in mice, a condition that can be completely reversed by eliminating the gut microbiota after antibiotic treatment, suggesting that the change in gut microbiota (dysbiosis) contributed to the development of CIPN induced by oxaliplatin

When multiple, the possibility of a genetic syndrome, such as neurofibromatosis 1 (NF1), needs to be considered (see Table 61.4 )

Bile acids as metabolic regulators

W., Binks, S
