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Fridovich in 1968 (McCord and Fridovich 1969), which catalyzes the dismutation reaction of superoxide radicals

However, once it enters cancer cells, once inside cancer cells, high intracellular GSH concentrations cleave the disulfide bond, converting the cyclic peptide into its linear form

Signs include: Hives or widespread rash beyond the injection site Swelling of face, lips, tongue, or throat Difficulty breathing or wheezing Rapid heartbeat Feeling faint or losing consciousness These symptoms require immediate medical attention

Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia and there is no existing personal conflicts of interest with any of the authors