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Kikuchi R, Sobue S, Murakami M, Ito H, Kimura A, Iwasaki T, et al

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177 The PI3K/Akt signaling pathway, a classic antioxidant pathway, plays a crucial role in HPH treatment by mediating antioxidation, anti-inflammation, inhibition of abnormal PASMC proliferation, and vasodilation while also protecting endothelial cells