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It has immune system effects

[Google Scholar] 8.De Marco R, Accordini S, Cerveri I, et al

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis
These receptors predominate on differentiated mature adipocytes, where they inhibit adenylyl cyclase activity and suppress lipolysis (12)
