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Comprehensive laboratory monitoring showed no clinically significant changes in vital signs, blood chemistry, or hormonal parameters

A.MabozaE.MeyerM.et al (2022)

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In the bile duct-ligated rats as well as in the occlusion-like syndrome and Budd-Chiarisyndrome rats [13,22,23,24,25], there was a consistent counteraction of the intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, aortal hypotension, and congested veins (i.e., reflecting trapped volumecongested inferior caval vein and superior mesenteric vein)
