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Subsequent research revealed that GHK has exceptionally high binding affinity for copper ions (Cu), forming a stable chelate complex (GHK-Cu) that is the biologically active form responsible for the peptide's remarkable effects

Second, and importantly for accountability, the 1889 Act for the first time required that an abstract of the annual accounts be sent to a central authority, namely the Local Government Board (LGB) (Ireland)

Durand P, Prost M, and Blache D (1997b)

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