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In this cascade, the activation of caspase-1 within the inflammasome complex leads to the cleavage of gasdermin-D (GSDMD) and the precursors of interleukin-1 (IL-1) and interleukin-18 (IL-18), marking the cell for pyroptotic death (Martinon et al., 2002
The human body is usually quick to adjust, though, so these symptoms should fade soon afterward
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
The cycle is complex and integrates several cellular processes, including release, uptake, synthesis, and metabolism of glutamate, GABA, and glutamine
