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Symptoms that warrant medical attention include severe or persistent headaches beyond one week, significant digestive distress, dizziness that doesn't resolve, skin rashes or allergic reactions, or any symptom that feels concerning for your body

Mitochondrial membrane potential assessment Mitochondrial membrane potential was determined using Tetrechloro-tetraethylbenzimidazol carbocyanine iodide (JC-1), following the protocols provided by the respective manufacturers (Beyotime, China)

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J Cell Physiol 237:18451856 [DOI] [PubMed] [Google Scholar] Joerger M, Huitema A, Illerhaus G, Ferreri A (2012) Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma