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& Abbott, B

25 In two randomized placebo-controlled trials, totaling 1257 patients with diabetic neuropathy, Sima and colleagues failed to find any significant electrophysiological change in patients treated with 500 or 1,000 mg ALC, although a significant improvement in the vibration perception threshold was reported

Subsequent, more restrictive recommendations limit carnitine supplements to those children with overdoses above 400 mg/kg

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