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More specifically, this may be observed with respect to certain genes, including Egr, Nos, Srf, Vegr, Akt1, Plc , and Kras genes (Vukojevic et al., 2018), all of which are responsible for the synthesis of factors necessary for a diverse set of processes

Endothelial dysfunction and inflammation are closely associated with the development of AS (Gimbrone and Garca-Cardea 2016

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But given the wide range of symptoms and the gradual rate at which they can appear, the condition is often overlooked or confused with something else