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Finally, as emphasized, BPC 157 beneficial effects include stimulation of egr-1 gene and its co-repressor gene naB2 [17], also responsible for cytokine and growth factor generation and thereby, early extracellular matrix (collagen) and blood vessel formation [17]

Severe deficiency can cause subacute combined degeneration of the spinal cord, which may not be fully reversible even after the deficiency is corrected