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Due to its inability to pass through membranes, GSH is transported into subcellular compartments (e.g., mitochondria, ER, nucleus, and peroxisomes) through distinct transporters [21,36,37]

Fuschiotti P (2020) T cells in SSc skin lesions: knowing your enemy

Upon entering the body, TLK199 undergoes esterase hydrolysis, which releases TLK117, its activated form that has anti-GST activity
