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Additionally, curcumin stimulates the Nrf2 pathway, promoting the production of protective enzymes such as heme oxygenase-1 (HO-1) and glutathione S-transferases (GSTs), which play crucial roles in mitigating oxidative stress [104]

Metformin and intermittent fasting mitigate high fat-fructose diet-induced liver and skeletal muscle injury through upregulation of mitophagy genes in rats

Finally, a glutamine-enriched diet is also shown to increase the abundance of beneficial Bifidobacteria in the jejunum of healthy weaned mice (194), and to decrease potentially harmful microorganisms in adult pigs (196)

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