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Int J Mol Sci, 2018

That said, a significant proportion of people in the United States are either deficient in vitamin B12 or lacking enough B12 for optimum health

It's frequently referenced alongside MOTS-c and NAD+ in research contexts, given the complementary nature of their respective pathway interactions - particularly how NNMT inhibition influences NAD+ availability in metabolic signalling studies

Pharmaceutics 13, 136 (2021)
