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doi: 10.1053/j.gastro.2020.05.048 Summary Keywords ozone therapy, immune response, SARS-CoV-2, COVID-19, microbiome, antioxidant, cytokine storm, anti-inflammatory Citation Cenci A, Macchia I, La Sorsa V, Sbarigia C, Di Donna V and Pietraforte D (2022) Mechanisms of Action of Ozone Therapy in Emerging Viral Diseases: Immunomodulatory Effects and Therapeutic Advantages With Reference to SARS-CoV-2

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The problem is that peripheral lipolysis alone, without addressing energy balance, appetite, or the upstream hormonal environment that drives fat accumulation, appears insufficient for meaningful clinical weight loss in humans