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Reported mild effects include: Commonly Reported Mild headaches: Some users report transient headaches, particularly in the first few days of use Anxiety or nervousness: A subset of users report increased anxiety, social anxiety, or a "jittery" sensation Overstimulation: Feeling mentally "wired," racing thoughts, or difficulty focusing despite cognitive goals Sleep disruption: Occasional reports of insomnia or vivid dreams if taken late in the day covered in depth in Dihexa, Sleep & Memory Consolidation: Vivid Dreams, REM & the 2026 Neuroscience Review, including parasomnia red flags and a practical dose-timing protocol Mood fluctuations: Some reports of subtle mood changes, though the direction (improvement vs

By identifying and avoiding symptom triggers, individuals with IC can actively manage their symptoms and improve their overall quality of life

Patients enrolled in randomized controlled trials do not represent the inflammatory bowel disease patient population