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128 Additionally, thalidomide inhibits M1 macrophage polarization by targeting the transcription factor IRF5, reduces the release of inflammatory signals, significantly reduces the secretion of the proinflammatory cytokines IL-12 and IFN-, and promotes intestinal mucosal healing
EXAMPLE 9 VASCULAR DISEASE PROPHYLAXIS Nonspecific esterases are present in the plasma that have a broad substrate specificity

195 ZhouH.YinC.ZhangZ.TangH.ShenW.ZhaX.et al (2020)
doi: 10.1016/j.ccell.2017.03.006 13 Sade-FeldmanMYizhakKBjorgaardSLRayJPde BoerCGJenkinsRWet al
