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Description
Here, we discovered that reducing the expression of the gene ech-6 encoding enoyl-CoA hydratase remitted fat diet-induced deleterious effects on lifespan in Caenorhabditis elegans , while a basal expression of ech-6 was important for survival under normal dietary conditions

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In each case, a typical lipid was incrementally replaced by a ferroptosis-relevant lipid, keeping all other aspects of lipid structures constant, while only changing the lipid structure of interest
