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Both intrinsic factors (such as signals from fibroblasts, keratinocytes, endocrine, inflammatory, and neuronal cells) and extrinsic factors (such as medication and UV rays) impact the recruitment of melanocytes, the number of dendrites, and the transfer of melanosomes to the keratinocytes (pigment transfer) [7]
294,295 However, some clinical trials have shown no benefit, 296,297 so the value of arginine supplementation needs to be further tested

10.1016/j.eplepsyres.2020.106469 129

PubMed, van der Meijden, Wisse P., et al
