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6 Conclusion and outlook Overall, the complex and multifaceted pathomechanisms of glaucoma, a complex degenerative disease of the optic nerve, call for a comprehensive approach to preventive and therapeutic strategies

The disease affects about 5 million Americans, mostly over age 40
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Research has indicated that dietary choices, particularly high-fat diets, significantly influence the gut microbiota, exacerbating DED symptoms through mechanisms such as decreased tear secretion, increased oxidative stress, and heightened apoptosis (Wu et al., 2020)
