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Researchers have developed dry powder inhalation systems and VIP conjugated with alpha-alumina nanoparticles (alpha-AN-VIP) that significantly reduced eosinophil counts, serum IgE, Th2 cytokines, and airway hyperresponsiveness in asthmatic animal models

IGF Binding Proteins and Bioavailability The mechanism underlying this enhanced potency relates to IGF-1's complex regulatory system involving IGF binding proteins (IGFBPs), a family of six high-affinity binding proteins (IGFBP-1 through IGFBP-6) that normally sequester the vast majority of circulating IGF-1 and regulate its bioavailability, half-life, and access to cell surface IGF-1 receptors

The retina, which is the light-sensitive layer at the back of the eye, contains a high concentration of zinc

doi: 10.1126/science.3029864 85 StockwellB