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The combined treatment of TMQ0153 and Gilteritinib demonstrates a synergistic effect in vitro and in vivo Complex II activity is notably elevated in FLT3-mutated AML patients, and its inhibition sensitizes these blasts to apoptosis [68]
Limitations of the Efficacy of C-Met Inhibitors A large number of clinical trials have proved that the safety of HGF or c-Met inhibitors is reliable
