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doi: 10.1681/ASN.2013121270.Epub2014May22 129 ZhouLFuPHuangXRLiuFLaiKNLanHY

In the context of T-cell acute lymphoblastic leukemia (T-ALL), nelfinavir has been shown to inhibit the NOTCH1 pathway by blocking -secretase activity through the inhibition of presenilin processing