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Months or even years after a viral infection, many patients find themselves trapped in a cycle of debilitating fatigue, unrefreshing sleep, and a racing heart

502 Moreover, neutrophils and NETs damage the glycocalyx of endothelial cells and increase endothelial permeability, which may further lead to dysregulated inflammation, impaired microcirculatory blood flow, inadequate tissue perfusion, and life-threatening organ failure

16 These molecules induce oxidative damage through unpaired valence-shell electrons that are highly unstable and reactive and have the ability to disrupt macromolecules, including proteins, lipids, carbohydrates, and nucleic acids

With ongoing advances in multi-omics profiling and machine learning techniques, biomarkers derived from iron metabolism are poised to become central pillars in the development of precision medicine strategies for Alzheimers disease