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A 52-week phase 2 trial on AMG133 in people with overweight and obesity is ongoing (NCT05669599)

The symptoms of RLS typically occur at night, making it difficult for individuals to get to sleep and causing interrupted sleep or sleep deprivation

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0.136 mol/L, p 10 by glutathione reductase and NADPH in physiological conditions and is dependent on the tissue type (Sies, 1999
