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RHONDA PATRICK: To measure the DR

The TRX antioxidant system is comprised of both TRX and thioredoxin reductase (27, 48, 175, 418)

These are typically cultured on top of transwell membranes with a neurobasal-based media underneath 141

Proposed Mechanism BPC-157 appears to work through multiple pathways: Maintaining vesicular integrity (affecting VMATs and dopamine transporters) Possibly occupying its own vesicular storage sites Competing for dopamine receptor binding Functionally substituting when dopaminergic neurons are lost This last property, essentially filling in for missing dopamine function, would explain why the peptide counteracts both receptor agonists (apomorphine) and antagonists (haloperidol, fluphenazine, clozapine, sulpiride) with equal effectiveness