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Mfn1 and Mfn2 promote the fusion of the outer mitochondrial membrane (OMM), while OPA1 is the major mitochondrial DNA (mtDNA) in mammals responsible for the fusion of the inner mitochondrial membrane (IMM) and remodeling of the mitochondrial cristae (Lee H
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The full-length parent (43 residues, ~4,963 Da) has been investigated under multiple INDs (RGN-259 / RGN-352 by RegeneRx Biopharmaceuticals) for dry-eye disease, neurotrauma, and wound healing
Abbott PV (2004) Classification, diagnosis and clinical manifestations of apical periodontitis
