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A hallmark of this differentiation process is the increased synthesis of phospholipids, particularly phosphatidylcholine (PC) (104), which supports the expansion of the intracellular membrane network, including the rough endoplasmic reticulum, where immunoglobulins are synthesized and assembled (105, 106) ( Figure 3 )

Current data suggest that resveratrol could improve specific metabolic variables in individuals with type 2 diabetes (138, 139), but more research is needed to assess its effect in individuals at risk for diabetes, including obese subjects with impaired glucose tolerance