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While rodent modelsparticularly those avoiding confounding physiological effects of high systemic chemotherapy doseshave provided valuable insight, validation of the mechanisms of CIPN in patients has been difficult not least because of the extensive co-morbidities usually present in this patient group
In NAFLD rats, resveratrol administration, either by itself or in conjunction with exercise, improved blood lipid profiles by reducing LDL, TC, and TG while markedly increasing HDL levels, as shown by Hajighasem et al
The other two break down more slowly, offering relief throughout the day
[DOI] [PubMed] [Google Scholar] 93.Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease
