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Keywords: trimethylamine N-oxide, gut-organ axis, cell death, biomarker, therapeutic strategies Introduction The gut is a vital organ of the host

For CTA and kaolin-intake studies, male Wistar rats (Janvier Labs, WistarRjHan:WI) were used

For example, IL-6 upregulates ZIP14 in hepatocytes and induces hypozincemia (decreased plasma zinc levels) in the acute phase response [31], an aspect of nutritional immunity
For detection, ImmPRESS HRP Horse Anti-Goat IgG Polymer Detection Kit (Vector Laboratories, Catalogue# MP7405) was used
