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When levels or signalling efficiency are disrupted, the effects can influence hormone balance throughout the body
The IFN--CXCL9/10-CXCR3 axis, central to CD8 + T cell recruitment and melanocyte destruction, has emerged as a key target (137)
The AGXT gene is expressed exclusively in hepatocytes and is localized to the peroxisomes
The NOAEL for these effects was 125 mg -tocopheryl acetate/kg body weight (Abdo et al., 1986)
