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Healthcare professionals should maintain vigilance regarding these intersecting risk factors when managing patients on GLP-1 receptor agonists

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Neuroendocrine Reset: It modulates the pineal gland, though the review notes a critical nuance: it may not directlystimulate melatonin secretion in all contexts but rather sensitizes pinealocytes or regulates the circadian machinery (e.g., Per1, Bmal1 genes)
Panniculectomy surgery may help eligible patients remove excess abdominal skin