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Description
The hydroxyl radical is generated by both aconitase inactivation and MPO activity, and promotes the formation of 8-oxo-dG

Introducing the reconstitution liquid too forcefully, using the wrong kind of liquid, or shaking the vial can physically shear these chains apart

Priebe W, Krawczyk M, Kuo MT, Yamane Y, Savaraj N, Ishikawa T

2013;304(8):E853E862
