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If you plan to discontinue tirzepatide, consider a gradual dose reduction over 8-12 weeks

Several groups are saying its time to translate their findings into human trials

Product Specifications Research Background Selective GH release Ipamorelin activates the GHS-R to trigger GH secretion in a dose-dependent manner while producing minimal effects on ACTH (and therefore cortisol) and prolactin secretion

At Beso, we prescribe from a range of weight loss peptides from the powerful GLP-1 receptor agonists (semaglutide, tirzepatide) that dominate appetite suppression, to growth hormone secretagogues (CJC-1295/Ipamorelin, Tesamorelin) that target fat metabolism and body composition, to metabolic peptides (AOD 9604) that directly accelerate fat breakdown