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Description
Safety and efficacy of long-term treatment with ephedrine, caffeine and an ephedrine/caffeine mixture

doi: 10.3390/jcm8111926 14

When dissolution was complete, the clear and colorless solution that results was stirred for about 15 minutes and then concentrated to dryness under vacuum, using a water bath that was maintained at less than about 70 C

Potential interactions depend on the medication and your dogs health status, so this is a veterinarian question
