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Readers exploring how the same fragment has been proposed to act in entirely different tissues the brain, for instance can see a parallel example of preclinical-mechanism reasoning in the discussion of the molecular mechanisms proposed for AOD-9604 in obese phenotypes, where the same caution about extrapolating from limited data applies

However, bioavailability through topical application remains limited compared to injectable delivery

doi: 10.1007/s00134-015-3924-9