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These results are in line with at least two previous studies
In this formulation, HA had a dual action in which it acted as a capping agent for the pores, and as a targeting ligand due to its degradation by hyaluronidase in the acidic environment of cancerous tissues

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Effect of an oral supplementation with a proprietary melon juice concentrate (Extramel) on stress and fatigue in healthy people: a pilot, double-blind, placebo-controlled clinical trial