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Retinal fluorescein and indocyanine green angiography is helpful to study the macula and screen for associated vasculitis, detect ischemic areas and preretinal, prepapillary or choroidal neovascular complications, and it may provide information about the etiology and be needed to assess the therapeutic response

Vitamin B-12 is a bioactive corrinoid compound used in experimental investigation of one-carbon metabolism, methylation pathways, and cellular redox.

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