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The ideal graft has not yet been found
type two affects the stability of the enzyme, which indirectly decreases the catalytic efficiency (structural determinant) ( Mutations A275T, R357W, A414V, L484P, and Y498C, far away from the active region, decrease activity by affecting the stability of CPT1A (Figure 8) (Table 1)
10.1186/s10194-018-0956-x J
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