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The study design, as a double-blind randomized controlled trial, is the most important strong point of this research

doi: 10.1016/j.phymed.2017.08.026

You will likely notice your wrinkles softening within two to five days, with full results appearing around 10 to 14 days after treatment

If fatigue persists or worsens over time, checking B12 levels, thyroid function, and other nutritional markers is warranted