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After treatment, brain tissues were harvested and evaluated for oxidative stress biomarkers (8-OHdG, MDA, GPx, GSH, GST, SOD), pro-inflammatory cytokines (MPO, NF-B, TNF-), ion transport enzymes (Na/K ATPase, Ca ATPase), neurotransmitter levels (dopamine, serotonin, AChE), and the apoptotic marker caspase-3

Thats why NAC is often discussed in relation tocellular resilience, meaning the ability of cells to adapt, recover, and maintain function under stress

Therefore, nutraceutical skin applications using collagen and antioxidants such as curcumin and glutathione demonstrate hopeful results for dermal antiaging effects, especially in estrogen-deficient skin