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The Met hydroxy analogs 2-hydroxy-4-(methylthio) butanoic acid (called HMB or HMTBa) and isopropyl ester of 2-hydroxy-4-(methylthio) butanoic acid (HMBi) have been widely used as a precursor of methionine in ruminant nutrition (Noftsger et al., 2003)

It forms in the veins found deep inside muscles and other tissues, and it can be fatal if left untreated

However, at higher doses and with more frequent dosing, the risk of having a child born with ASD may actually increase, per that same study

This direct delivery means your body doesnt have to work hard to absorb it, unlike when you take pills or eat foods rich in B12