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In some instances, its use in dogs is off-label (extra-label), which means that it is used outside the scope of the original product label, but based on clinical evidence and veterinary professional judgment

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Although the majority of studies on the microbiotas of people with endometriosis focus on the vaginal, cervical, uterine, or gut microbiotas, studies have profiled the bacteria found in endometriotic lesions 31,77 and extracellular vesicles (ECVs) isolated from peritoneal fluid of patients with endometriomas 78 by 16S sequencing, demonstrating that bacteria can be found in disease lesions and ECVs