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Description
With regard to clinical studies, exclusive nuclear IGF-1R was associated with response to various IGF-1R Abs in patients with sarcoma, shown by improved PFS and OS, suggesting IGF-1R nuclear translocation could also be a biomarker of IGF pathway activation [130]

(2006) A Toolbox of GFP technologies: monitoring protein folding, expression and solubility

This analog has been engineered with the express purpose of increasing biological activity

They also experience cognitive difficulties and are hypersensitive to external stimuli (11)
